【关键词】细胞色素P450;细胞系，C3A；脂肪肝，非酒精性；细胞增殖TheexpressionofCYP2E1anditseffectontheproliferationofC3AhepatocytecelllineLIUTian-hui,XUYou-qing,YOUHong,XUYong,CONGMin,WANGPing,JIAJi-don…
【关键词】血管紧张素原；肾素；肝纤维化ExpressionofangiotensinogenduringdevelopmentandspontaneousreversalofhepaticfibrosisYANGLiu,LIUHai-lin,HUOLi,WANGLei.【Keywords】Angiotensinogen;Renin;Liverfibrosi…
【关键词】癌，肝细胞；免疫毒素类；蜂毒肽；荧光抗体蛋白技术ExpressionofmelittintaggedwithgreenfluorescentproteinanditsuseinhepatocellularcarcinomatreatmentCHENJiang,WANGWei-yu,LUZhi-xian,CHENGHua-li,CH…
【摘要】目的观察Rho/Rho激酶(ROCK)信号转导通路抑制剂——法舒地尔，对肝星状细胞（HSC）黏附、迁移和增殖的影响。方法将培养的HSC分为以下5组：对照组；法舒地尔12.5μmol/L组；法舒地尔25μmol/L组；法舒地尔50μ…
【摘要】目的了解内毒素受体在肝星状细胞活化中的变化和作用。方法分离正常大鼠的肝星状细胞，以逆转录聚合酶链反应法检测其在体外培养过程中内毒素受体（CD14和TLR4）mRNA的表达变化。以细胞免疫染色法检测肝星状细…
【关键词】肝炎病毒，乙型；RNA干扰；小干扰RNAInhibitionofHBVreplicationandexpressionbyRNAiWANGYue,NIUJun-qi,DINGYan-hua,WANGFeng【Keywords】HepatitisBvirus;RNAinterference;SmallinterferingRNA【Firstaut…
【关键词】癌，肝细胞；脱氧寡核苷酸，反义TargetingtheMDM2geneusingantisenseoligonucleotidetoinducecellapoptosisinhumanhepatoblastomacelllineHepG2TENGGuang-ju,TENGGuang-shou,LIBao-sen,ZOUZheng-sheng,ZHA…
【关键词】放射摄影术；肝脏;图像增强；衍射增强成像Valuesofthediffraction-enhancedimaging(DEI)techniqueinliverdiseasediagnosisPENGYi-feng,CHENShao-liang.【Keywords】Radiography;Liver;Imageenhancement;Di…
【关键词】瘦素；瘦素受体；癌，肝细胞ApreliminarystudyoftherelationshipbetweenleptinanditsreceptorandprimaryhepatocellularcarcinomaSHENLei,ZHOUJing,LEIWei,WEIYun,SHENZhi-xiang,LUOHe-sheng.【Keywords】L…
【关键词】肝纤维化；胶原；转化生长因子β；激动素EffectofkinetinonexpressionofcollagentypeI,III,IVandtransforminggrowthfactorβ1inliversofratswithhepaticfibrosisZHANGZhen-gang,TIANDe-ying,ZHOUJian,MAXi…
【摘要】目的观察己酮可可碱对非酒精性脂肪性肝炎大鼠肝脏核因子-κB（NF-κB）信号通路及胰岛素受体底物（IRS）-1、IRS-2和葡萄糖转运子2（GLUT2）表达的影响。方法24只SD大鼠高脂饮食饲养4周后，随机分为模型组和干…
【摘要】目的观察肝纤维化大鼠的肥大细胞（MC）数量变化和蛋白酶激活受体-2（PAR-2）在肝脏中表达及其与肝纤维化的关系。方法建立大鼠肝纤维化模型，以甲苯胺蓝染色显示MC，运用碱水解法测定肝脏羟脯氨酸含量，采用逆…
【摘要】目的应用短发夹状RNA介导的RNA干扰研究乙型肝炎病毒X基因（HBX）和三氧化二砷（As2O3）对HepG2细胞p53表达和活性的影响。方法以2μmol/LAs2O3处理HepG2细胞和表达HBX的HepG2-X，以未处理细胞为对照，提取细胞…
【关键词】脂肪肝，酒精性；胰岛素抗药性；吡格列酮PreventiveeffectsofpioglitazoneonratfattyliverinducedbyahighfatdietXUPing,LIYou-ming,YUChao-hui,XULei,XUGen-yun.【Keywords】Fattyliver,nonalcoholic;Insu…
【关键词】肝纤维化；金属蛋白酶1组织抑制剂；基质金属蛋白酶；罗格列酮Effectofrosiglitazoneonmetalloproteinasetissueinhibitor-1inCCl4-inducedliverfibrosisinratsZHOUXi-han,LIMing-gui,LXiao-hong,WUXiang-yu…
【关键词】癌,肝细胞；NF-κB；细胞凋亡；G(D3)神经节苷脂；阿霉素GangliosideGD3enhancestheanti-tumoreffectofdoxorubicinonhepatomacellsWANGJian-hong,HUANGZhi-ming,WUJian-sheng,CHENXiang-rong,JINShu-qing,H…
【关键词】癌，肝细胞；细胞凋亡；环氧合酶-2；柴胡皂甙Effectofsaikosaponins-doncyclooxygenase-2expressionofhumanhepatocellularcarcinomacelllineSMMC-7721HEShui-xiang,LUOJin-yan,ZHAOGang,XUJun-li,WANGYan-…
【关键词】肝纤维化；雌激素类；抗内皮细胞抗体Thesignificanceofanti-endothelialcellantibodyexpressioninratliverfibrosistreatedwithestrogenDENGJing-yu,HESheng,CHENBo.【Keywords】Hepaticfibrosis;Estrogens…
【关键词】肝肿瘤；亚砷酸盐类；兔；射频TheeffectofradiofrequencyablationcombinedwitharsenitesonrabbitliverVX2tumorsZHANGMeng-hui,KONGXian-bing,WANGQiao-ling,HUANGXiao-ling,WANGHui,GUOAi-hong.【Keywords…
【关键词】肝纤维化；转化生长因子β；疫苗；基质金属蛋白酶；金属蛋白酶类组织抑制剂EffectofTGFβ1vaccineontheexpressionofMMP-2andTIMP-2inratswithliverfibrosisLUMing-qin,CHENYong-ping,PANChen-wei,WANGXiao…
